3,4,5-trisubstituted aryl nitrone compounds and pharmaceutical compositions containing the same

14 Disclosed are 3,4,5-trisubstituted aryl nitrone compoundsd and pharmaceutical compositions containing such compounds. The 3,4,5-trisubstituted aryl nitrone compounds have formula (I); where R-Rare as defined in the specification. The disclosed compositions are useful as therapeutics for inflammat...

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Hauptverfasser: Waterbury, L. David, Wilcox, Allan L, Carney, John M, Mavandadi, Farah, Danielzadeh, Albert
Format: Patent
Sprache:eng
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Zusammenfassung:14 Disclosed are 3,4,5-trisubstituted aryl nitrone compoundsd and pharmaceutical compositions containing such compounds. The 3,4,5-trisubstituted aryl nitrone compounds have formula (I); where R-Rare as defined in the specification. The disclosed compositions are useful as therapeutics for inflammation-related conditions in mammals, such as arthritis, and as analytical reagents for detecting free radicals.