Method of treating cancer

The present invention relates to methods of treating cancer using a combination of a compound which is an antineoplastic agent and a compound which is a inhibitor of prenyl-protein transferase, which methods comprise administering to said mammal, either sequentially in any order or simultaneously, a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rosen, Neal, Sepp-Lorenzino, Laura, Moasser, Mark M, Oliff, Allen I, Gibbs, Jackson B, Kohl, Nancy, Graham, Samuel L, Prendergast, George C
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to methods of treating cancer using a combination of a compound which is an antineoplastic agent and a compound which is a inhibitor of prenyl-protein transferase, which methods comprise administering to said mammal, either sequentially in any order or simultaneously, amounts of at lest two therapeutic agents selected from a group consisting of a compound which is an antineoplastic agent and a compound which is an inhibitor or prenyl-protein transferase. The invention also relates to methods of preparing such compositions.