Treatment of metastatic disease

The present invention is directed to compounds and methods for the treatment of metastatic disease. The compounds of this invention have specificity for EphA2, an epithelial cell tyrosine kinase that is overexpressed in metastatic tumor cells. The compounds used in accordance with this invention may...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kinch, Michael S, Zantek, Nicole D, Hein, Patrick W
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention is directed to compounds and methods for the treatment of metastatic disease. The compounds of this invention have specificity for EphA2, an epithelial cell tyrosine kinase that is overexpressed in metastatic tumor cells. The compounds used in accordance with this invention may be provided in a pharmaceutical composition for treatment of metastatic disease.