Amine-derivatized nucleosides and oligonucleosides

Nucleotides and oligonucleosides functionalized to include alkylamino functionality, and derivatives thereof. In certain embodiments, the compounds of the invention further include steroids, reporter molecules, reporter enzymes, lipophilic molecules, peptides or proteins attached to the nucleotides...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cook, Phillip Dan, Manoharan, Muthiah, Guinosso, Charles J
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Nucleotides and oligonucleosides functionalized to include alkylamino functionality, and derivatives thereof. In certain embodiments, the compounds of the invention further include steroids, reporter molecules, reporter enzymes, lipophilic molecules, peptides or proteins attached to the nucleotides through the alkylamino group.