Microfluidic system and methods of use

This invention relates to a novel microfluidic device and methods of using this device to conduct in vitro studies on the reaction and effects of various compounds on cells. More particularly, it relates to a method for using stop flow in a microfluidic system to study the effect of compounds on ind...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Harrison, Daniel Jed, Andersson, Per, Li, Paul C. H, Szarka, Roderick, Smith, Richard, Salimi-Moosavi, Hossein
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:This invention relates to a novel microfluidic device and methods of using this device to conduct in vitro studies on the reaction and effects of various compounds on cells. More particularly, it relates to a method for using stop flow in a microfluidic system to study the effect of compounds on individual cells. It also provides a method for observing the effects of candidate compounds on leukocyte rolling.