Surface coating spatially controlled patterns

The invention provides a biodegradable and biocompatible polymer article having a surface wherein a biologically active ligand is provided on said surface in a spatially controlled pattern. The pattern may be formed using a poly(dimethyl siloxane) mold. The biologically active ligand may be attached...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shakesheff, Kevin, Patel, Nikin, Cannizzaro, Scott M, Langer, Robert S
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention provides a biodegradable and biocompatible polymer article having a surface wherein a biologically active ligand is provided on said surface in a spatially controlled pattern. The pattern may be formed using a poly(dimethyl siloxane) mold. The biologically active ligand may be attached to the polymer article by a biotin-avidin-biotin linkage.