Morphological mutants of filamentous fungi

1. Field of the Invention The present invention relates to methods of obtaining a mutant cell from a filamentous fungal parent cell, comprising: (a) obtaining mutant cells of the parent cell; (b) identifying the mutant cell which exhibits a more restricted colonial phenotype and/or a more extensive...

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Bibliographische Detailangaben
Hauptverfasser: Shuster, Jeffrey R, Royer, John C
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:1. Field of the Invention The present invention relates to methods of obtaining a mutant cell from a filamentous fungal parent cell, comprising: (a) obtaining mutant cells of the parent cell; (b) identifying the mutant cell which exhibits a more restricted colonial phenotype and/or a more extensive hyphal branching than the parent cell; and (c) identifying the mutant cell which has an improved property for production of a heterologous polypeptide than the parent cell, when the mutant and parent cells are cultured under the same conditions.