Interface for iontophoresis

1. Field of the Invention A hydrophilic membrane having a low adsorptivity for a protein is disposed, as an interface, on a side to be contacted with a skin, and a drug such as a physiologically active peptide is transdermally delivered by iontophoresis. The membrane has an adsorptivity for a protei...

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Bibliographische Detailangaben
Hauptverfasser: Yanai, Shigeo, Iga, Katsumi, Matsumoto, Yukihiro, Higo, Naruhito
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:1. Field of the Invention A hydrophilic membrane having a low adsorptivity for a protein is disposed, as an interface, on a side to be contacted with a skin, and a drug such as a physiologically active peptide is transdermally delivered by iontophoresis. The membrane has an adsorptivity for a protein of not greater than 10 g/cm. The thickness of the membrane is about 10 to 200 m, and the porosity of the membrane is about 60 to 90%. Such membrane includes a hydrophilized fluororesin membrane, a hydrophilized polysulfone membrane and a hydrophilized cellulose derivative membrane.