Hydroxamic and carboxylic acid derivatives having MMP and TNF inhibitory activity

Hydroxamic and carboxylic acid derivatives having MMP and TNF inhibitory activity

This invention relates to hydroxamic and carboxylic acid derivatives, and to their use in medicine. 4-(4-(-Chlorophenyl)piperazin-1-yl)sulfonylmethyl)-tetrahydor yran-4-carboxylic acid and the corresponding N-hydroxy amide, and derivatives thereof, are useful as therapeutic agents.

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Bibliographische Detailangaben
Hauptverfasser: Baxter, Andrew Douglas, Owen, David Alan, Watson, Robert John
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:This invention relates to hydroxamic and carboxylic acid derivatives, and to their use in medicine. 4-(4-(-Chlorophenyl)piperazin-1-yl)sulfonylmethyl)-tetrahydor yran-4-carboxylic acid and the corresponding N-hydroxy amide, and derivatives thereof, are useful as therapeutic agents.