Heterocyclic glycyl -alanine derivatives

The present invention relates to pharmaceutical agents (compounds) which are useful as integrin antagonists and as such are useful in pharmaceutical compositions and in methods for treating conditions mediated by by inhibiting or antagonizing integrins. The present invention relates to a class of co...

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Bibliographische Detailangaben
Hauptverfasser: Chandrakumar, Nizal Samuel, Desai, Bipinchandra Nanubhai, Devadas, Balekudru, Gasiecki, Alan Frank, Huff, Renee, Khanna, Ish K, Malecha, James W, Miyashiro, Julie M, Rao, Shashidhar N, Rico, Joseph Gerace, Rogers, Thomas Edward, Ruminski, Peter Gerrard, Russell, Mark Andrew, Yu, Yi
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to pharmaceutical agents (compounds) which are useful as integrin antagonists and as such are useful in pharmaceutical compositions and in methods for treating conditions mediated by by inhibiting or antagonizing integrins. The present invention relates to a class of compounds represented by the Formula I or a pharmaceutically acceptable salts thereof, pharmaceutical compositions containing such compounds and methods of treating conditions mediated by the integrin.