Inhibition of HIV replication using soluble Tat peptide analogs

The present invention relates to nucleic acid and peptide compositions which inhibit HIV replication in a mammalian cell. The present invention further relates to methods of inhibiting HIV replication in a mammalian cell by administering the compositions of the invention. Methods and compositions fo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kashanchi, Fatah, Sadaie, Mohammad Reza, Brady, John
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to nucleic acid and peptide compositions which inhibit HIV replication in a mammalian cell. The present invention further relates to methods of inhibiting HIV replication in a mammalian cell by administering the compositions of the invention. Methods and compositions for inhibiting replication of HIV in a mammalian cell. The compositions can be a peptide, or a nucleic acids encoding a peptide, which inhibits transactivation of the HIV long terminal repeat.