Water-soluble amide derivatives of polyene macrolides and preparation and uses thereof
2.1 Field of the Invention The present invention provides two new classes of polyene macrolide amide derivatives useful for treating or preventing fungal infections. The new polyene macrolide amide derivatives exhibit antifungal activity and are more water-soluble than conventional polyene antibioti...
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Format: | Patent |
Sprache: | eng |
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Zusammenfassung: | 2.1 Field of the Invention
The present invention provides two new classes of polyene macrolide amide derivatives useful for treating or preventing fungal infections. The new polyene macrolide amide derivatives exhibit antifungal activity and are more water-soluble than conventional polyene antibiotics, such as amphotericin B and amphotericin B methyl ester. |
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