Process for preparing optically active cyanohydrins and secondary products

The invention relates to a process for preparing optically active cyanohydrins using a highly active (R)-hydroxynitrile lyase extract. The present invention relates to a process for preparing optically active cyanohydrins of the formula (II), by reacting an aldehyde of the formula (I) with HCN in a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kirschbaum, Bettina, Wilbert, Goetz, Effenberger, Franz
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to a process for preparing optically active cyanohydrins using a highly active (R)-hydroxynitrile lyase extract. The present invention relates to a process for preparing optically active cyanohydrins of the formula (II), by reacting an aldehyde of the formula (I) with HCN in a water-immiscible organic solvent in the presence of water, in the absence or presence of a buffer, in the presence of a (R)-hydroxynitrile lyase, where X, Y and Z in formula (II) have the same meaning as in formula (I), independently of each other are identical or different and are H, F, Cl, Br, I, OH, O(C-C-alkyl), OCOCH, NHCOCH, NOor C-C-alkyl.