3-oxopropane-1-sulphonic acids and sulphonates

The present invention relates to 3-oxopropane-1-sulphonic acids and sulphonates, optionally in enantiomerically enriched form. The invention further relates to the use or enantiomerically enriched 3-oxopropane-1-sulphonic acids and sulphonates in the resolution or mixtures or enantiomers, for instan...

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Bibliographische Detailangaben
Hauptverfasser: Wijnberg, Hans, Pouwer, Kees, Nieuwenhuijzen, Jose, Vries, Ton Rene
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to 3-oxopropane-1-sulphonic acids and sulphonates, optionally in enantiomerically enriched form. The invention further relates to the use or enantiomerically enriched 3-oxopropane-1-sulphonic acids and sulphonates in the resolution or mixtures or enantiomers, for instance racemic mixtures. The invention relates in particular to (d)- and (l)-enantiomers of 3-oxopropane-1-sulphonic acids of general formula I or a salt thereof: The invention relates to 1,3-disubstituted-3-oxopropane-1-sulfonic acids and sulfonates and enantiomerically inriched forms thereof. The invention further relates to the use of these enantiomerically inriched compounds to resolve mixtures of enantiomers, in particular mixtures of enantiomers of amino-functionalized compounds.