Fusobacterium necrophorum vaccine and method for making such vaccine

The present invention relates to a vaccine, and an in-vitro method for developing such a vaccine, for establishing resistance to bacteria that is responsible for footrot and liver abscesses in the bovine species. The present invention relates to a method of producing a vaccine for the prevention of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liem, Adrian, Anderson, Gary A, Stine, Douglas L
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to a vaccine, and an in-vitro method for developing such a vaccine, for establishing resistance to bacteria that is responsible for footrot and liver abscesses in the bovine species. The present invention relates to a method of producing a vaccine for the prevention of bacterial infections, comprising isolating the bacteria from a bovine species, growing the bacteria in a suitable growth medium for a period equal to between about 10 hours and about 18 hours so as to achieve a bacterial population equal to at least 1×10CFU/ml, terminating the growth, and using a whole cell culture to form the vaccine. Additionally, the present invention relates to the vaccine comprised of a killed whole cell population of the bacteria taken from a bovine. The present invention further relates to a method for preventing footrot and liver abscesses caused by bacteria.