Generating replicating molecules in vivo

The present invention relates to circular and replicative DNA molecules which can be used in gene therapy. The invention also describes a particularly efficient method for their generation in situ from a corresponding viral vector. The invention discloses circular and replicating DNA molecules, usef...

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Bibliographische Detailangaben
Hauptverfasser: Perricaudet, Michel, Yeh, Patrice, Leblois-Prehaud, Hélène
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to circular and replicative DNA molecules which can be used in gene therapy. The invention also describes a particularly efficient method for their generation in situ from a corresponding viral vector. The invention discloses circular and replicating DNA molecules, useful in gene therapy, as well as a particularly efficient method for generating them in situ from a viral vector.