Process for producing glycolytic metabolism regulators

This invention relates to foods or drugs which are characterized by containing fructose-6-phosphate-2-kinase inhibitors, such as itaconic acid and its salts, as active ingredients, and which exert antiobesity, antidiabetic, and antilipemic effects due to the existence of inhibitors that function to suppress the glycolytic pathway and the activity of phosphofructokinase, a regulatory enzyme of the glycolytic pathway. The invention also relates to a method for preparing these foods or drugs. A food or beverage containing an effective amount of a fructose-6-phosphate-2-kinase inhibitor which is safe and effective in vivo, such as itaconic acid, and a pharmaceutical composition containing the inhibitor as an active ingredient are disclosed. This food, beverage or pharmaceutical composition safely exerts an antiobesity, antidiabetic, and an antilipemic effect.