Remedies for joint diseases
This application is a 371 of PCT/JP00/01487 filed Mar. 10, 2000. The present invention provides an agent for treatment of arthritic diseases such as rheumatoid arthritis that has for its active ingredient a complex of hyaluronic acid and zinc. This complex synergistically inhibits proliferation of s...
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| Format: | Patent |
| Sprache: | eng |
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| Zusammenfassung: | This application is a 371 of PCT/JP00/01487 filed Mar. 10, 2000.
The present invention provides an agent for treatment of arthritic diseases such as rheumatoid arthritis that has for its active ingredient a complex of hyaluronic acid and zinc. This complex synergistically inhibits proliferation of synovial cells and suppresses matrix metalloproteinase MMP-9, which is produced by synovial cells, as compared with its constituents, hyaluronic acid and zinc, alone. |
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