Process for the preparation of N-carboxyanhydrides
The invention relates to an improved process for the preparation of N-carboxyanhydrides from the corresponding amino acids and phosgene, diphosgene or triphosgene. The invention relates to an improved process for the preparation of N-carboxyanhydrides by reaction of the corresponding amino acid or o...
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| Format: | Patent |
| Sprache: | eng |
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| Zusammenfassung: | The invention relates to an improved process for the preparation of N-carboxyanhydrides from the corresponding amino acids and phosgene, diphosgene or triphosgene.
The invention relates to an improved process for the preparation of N-carboxyanhydrides by reaction of the corresponding amino acid or one of its salts with phosgene, diphosgene and/or triphosgene in a solvent medium, characterized in that at least a portion of the reaction is carried out under a pressure of less than 1000 mbar. The N-carboxyanhydrides are thus obtained with better yields and an improved purity. |
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