3,3-Biarylpiperidine and 2,2-biarylmorpholine derivatives

This invention relates to 3,3-biarylpiperidine and 2,2-biarylmorpholine derivatives which have utility as ligands for opioid receptors. The present invention relates to compounds of the formula I, wherein Z, Z, X, Q, R, Rand Rare defined as in the specification, pharmaceutical compositions containin...

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Hauptverfasser: Liras, Spiros, Allen, Martin P, Segelstein, Barbara E
Format: Patent
Sprache:eng
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Zusammenfassung:This invention relates to 3,3-biarylpiperidine and 2,2-biarylmorpholine derivatives which have utility as ligands for opioid receptors. The present invention relates to compounds of the formula I, wherein Z, Z, X, Q, R, Rand Rare defined as in the specification, pharmaceutical compositions containing such compounds the use of such compounds to treat neurological and gastrointestinal disorders.