Bone putty and method

This invention pertains to a bone matrix suspension in forms suitable for surgical grafting or other medical uses and a method for making same. A method for the preparation of bone gel and bone putty which comprises producing a viscous supernatant by dissolving demineralized bone matrix in water or...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gendler, El, Gendler, Eli, Gendler, Simon
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:This invention pertains to a bone matrix suspension in forms suitable for surgical grafting or other medical uses and a method for making same. A method for the preparation of bone gel and bone putty which comprises producing a viscous supernatant by dissolving demineralized bone matrix in water or a solution comprising water and at least one component normally found in human blood serum, at a temperature above about 25° C. Agitation and/or ultrasound or pressure accelerates dissolution of the demineralized bone. The resulting viscous supernatant is cooled, then mixed with demineralized or non-demineralized bone matrix particles to form a gel-like suspension or putty-like material.