Reagent and method for the permeabilization and identification of erythrocytes

The present invention relates to new reagents and a new permeabilization process for erythrocytes as well as its use in the identification of foetal erythrocytes by a new immuno-marking method. A process for permeabilizing erythrocytes in which the erythrocytes are subjected successively to the acti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Agthoven, André Van, Fornelli, Christine
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to new reagents and a new permeabilization process for erythrocytes as well as its use in the identification of foetal erythrocytes by a new immuno-marking method. A process for permeabilizing erythrocytes in which the erythrocytes are subjected successively to the action of(a) a fixing agent containing an aliphatic aldehyde and oligosaccharide,(b) a permeabilizing agent containing a detergent and an oligosaccharide,kit for permeabilizing erythrocytes, kit for immuno-marking fetal erythrocytes, and a process for identifying fetal erythrocytes by immuno-marking.