Process for preparing optically active 1-amino-4-(hydroxymethyl) cyclopent-2-ene derivatives

Process for preparing optically active 1-amino-4-(hydroxymethyl) cyclopent-2-ene derivatives

The present invention relates to a novel process for preparing enantiomerically enriched 1-amino-4-(hydroxymethyl)cyclopent-2-ene derivatives of the general formulae: The invention discloses a new method for producing enantiomer-enriched 1-amino-4-(hydroxymethyl)-cyclopent-2-ene derivatives of the g...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Brieden, Walter, Etter, Kay-Sara, Petersen, Michael
Format: Patent
Sprache:eng
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator Brieden, Walter
Etter, Kay-Sara
Petersen, Michael
description The present invention relates to a novel process for preparing enantiomerically enriched 1-amino-4-(hydroxymethyl)cyclopent-2-ene derivatives of the general formulae: The invention discloses a new method for producing enantiomer-enriched 1-amino-4-(hydroxymethyl)-cyclopent-2-ene derivatives of the general formulae (I) and (II) in which Ris hydrogen or a possibly substituted Calkyl radical, aryl radical or cycloalkyl radical and Ris acyl. According to said method a racemic 1-amino-4-(hydroxymethyl)-cyclopent-2-ene derivative of general formula (III), in which Rhas the meaning given above, is converted using a hydrolase and in the presence of an acylation agent
format Patent
fullrecord <record><control><sourceid>uspatents_EFH</sourceid><recordid>TN_cdi_uspatents_grants_06524844</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>06524844</sourcerecordid><originalsourceid>FETCH-uspatents_grants_065248443</originalsourceid><addsrcrecordid>eNqNy7EKwjAQgOEsDqK-w406BLSm4i6Ko4OjIEd6bQNpLlxiMW-vBR_A6Vv-f64eN2FLKUHLAlEoorjQAcfsLHpfAG12I8FO4-ACa6PXfWmE32Wg3Be_AVus50gh60pTIGhI3IjTlJZq1qJPtPq5UHA5309X_UoR83dJz05wYnuoK3M0Zv9H8gFKZTyE</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Process for preparing optically active 1-amino-4-(hydroxymethyl) cyclopent-2-ene derivatives</title><source>USPTO Issued Patents</source><creator>Brieden, Walter ; Etter, Kay-Sara ; Petersen, Michael</creator><creatorcontrib>Brieden, Walter ; Etter, Kay-Sara ; Petersen, Michael ; Lonza AG</creatorcontrib><description>The present invention relates to a novel process for preparing enantiomerically enriched 1-amino-4-(hydroxymethyl)cyclopent-2-ene derivatives of the general formulae: The invention discloses a new method for producing enantiomer-enriched 1-amino-4-(hydroxymethyl)-cyclopent-2-ene derivatives of the general formulae (I) and (II) in which Ris hydrogen or a possibly substituted Calkyl radical, aryl radical or cycloalkyl radical and Ris acyl. According to said method a racemic 1-amino-4-(hydroxymethyl)-cyclopent-2-ene derivative of general formula (III), in which Rhas the meaning given above, is converted using a hydrolase and in the presence of an acylation agent</description><language>eng</language><creationdate>2003</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6524844$$EPDF$$P50$$Guspatents$$Hfree_for_read</linktopdf><link.rule.ids>230,308,780,802,885,64039</link.rule.ids><linktorsrc>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6524844$$EView_record_in_USPTO$$FView_record_in_$$GUSPTO$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Brieden, Walter</creatorcontrib><creatorcontrib>Etter, Kay-Sara</creatorcontrib><creatorcontrib>Petersen, Michael</creatorcontrib><creatorcontrib>Lonza AG</creatorcontrib><title>Process for preparing optically active 1-amino-4-(hydroxymethyl) cyclopent-2-ene derivatives</title><description>The present invention relates to a novel process for preparing enantiomerically enriched 1-amino-4-(hydroxymethyl)cyclopent-2-ene derivatives of the general formulae: The invention discloses a new method for producing enantiomer-enriched 1-amino-4-(hydroxymethyl)-cyclopent-2-ene derivatives of the general formulae (I) and (II) in which Ris hydrogen or a possibly substituted Calkyl radical, aryl radical or cycloalkyl radical and Ris acyl. According to said method a racemic 1-amino-4-(hydroxymethyl)-cyclopent-2-ene derivative of general formula (III), in which Rhas the meaning given above, is converted using a hydrolase and in the presence of an acylation agent</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2003</creationdate><recordtype>patent</recordtype><sourceid>EFH</sourceid><recordid>eNqNy7EKwjAQgOEsDqK-w406BLSm4i6Ko4OjIEd6bQNpLlxiMW-vBR_A6Vv-f64eN2FLKUHLAlEoorjQAcfsLHpfAG12I8FO4-ACa6PXfWmE32Wg3Be_AVus50gh60pTIGhI3IjTlJZq1qJPtPq5UHA5309X_UoR83dJz05wYnuoK3M0Zv9H8gFKZTyE</recordid><startdate>20030225</startdate><enddate>20030225</enddate><creator>Brieden, Walter</creator><creator>Etter, Kay-Sara</creator><creator>Petersen, Michael</creator><scope>EFH</scope></search><sort><creationdate>20030225</creationdate><title>Process for preparing optically active 1-amino-4-(hydroxymethyl) cyclopent-2-ene derivatives</title><author>Brieden, Walter ; Etter, Kay-Sara ; Petersen, Michael</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-uspatents_grants_065248443</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2003</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Brieden, Walter</creatorcontrib><creatorcontrib>Etter, Kay-Sara</creatorcontrib><creatorcontrib>Petersen, Michael</creatorcontrib><creatorcontrib>Lonza AG</creatorcontrib><collection>USPTO Issued Patents</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Brieden, Walter</au><au>Etter, Kay-Sara</au><au>Petersen, Michael</au><aucorp>Lonza AG</aucorp><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Process for preparing optically active 1-amino-4-(hydroxymethyl) cyclopent-2-ene derivatives</title><date>2003-02-25</date><risdate>2003</risdate><abstract>The present invention relates to a novel process for preparing enantiomerically enriched 1-amino-4-(hydroxymethyl)cyclopent-2-ene derivatives of the general formulae: The invention discloses a new method for producing enantiomer-enriched 1-amino-4-(hydroxymethyl)-cyclopent-2-ene derivatives of the general formulae (I) and (II) in which Ris hydrogen or a possibly substituted Calkyl radical, aryl radical or cycloalkyl radical and Ris acyl. According to said method a racemic 1-amino-4-(hydroxymethyl)-cyclopent-2-ene derivative of general formula (III), in which Rhas the meaning given above, is converted using a hydrolase and in the presence of an acylation agent</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_uspatents_grants_06524844
source USPTO Issued Patents
title Process for preparing optically active 1-amino-4-(hydroxymethyl) cyclopent-2-ene derivatives
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-21T10%3A18%3A41IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-uspatents_EFH&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Brieden,%20Walter&rft.aucorp=Lonza%20AG&rft.date=2003-02-25&rft_id=info:doi/&rft_dat=%3Cuspatents_EFH%3E06524844%3C/uspatents_EFH%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true