Process for preparing optically active 1-amino-4-(hydroxymethyl) cyclopent-2-ene derivatives

The present invention relates to a novel process for preparing enantiomerically enriched 1-amino-4-(hydroxymethyl)cyclopent-2-ene derivatives of the general formulae: The invention discloses a new method for producing enantiomer-enriched 1-amino-4-(hydroxymethyl)-cyclopent-2-ene derivatives of the general formulae (I) and (II) in which Ris hydrogen or a possibly substituted Calkyl radical, aryl radical or cycloalkyl radical and Ris acyl. According to said method a racemic 1-amino-4-(hydroxymethyl)-cyclopent-2-ene derivative of general formula (III), in which Rhas the meaning given above, is converted using a hydrolase and in the presence of an acylation agent