Multi-chip packaging structure

1. Field of the Invention A multi-chip packaging structure in which a plurality of chips is aligned on two surfaces of a substrate and the substrate has an opening. The chip located on the second surface of the substrate has center bonding pads arrangement. These bonding pads are connected to the conductive connections on the first surface of the substrate by means of the opening. The other chips are attached to the first surface of the substrate and have a plurality of bonding pads connected to the conductive connections on the first surface of the substrate by wire bonding or flip-chip bonding. Furthermore, a heat sink is attached to the back surface of the chip located on the second surface in order to improve the heat dissipation performance of the package.