Polylactic acid scleral plug

The present invention relates to a scleral plug made from a novel composition with a view to treating or preventing vitreoreti disorders. A scleral plug which releases a drug accurately in a specified amount. The scleral plug is formed from a blend of a high-molecular weight polylactic acid having a...

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Bibliographische Detailangaben
Hauptverfasser: Ogura, Yuichiro, Kunou, Noriyuki, Ota, Atsutoshi
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to a scleral plug made from a novel composition with a view to treating or preventing vitreoreti disorders. A scleral plug which releases a drug accurately in a specified amount. The scleral plug is formed from a blend of a high-molecular weight polylactic acid having a molecular weight of 40,000 or higher and a low-molecular weight polylactic acid having a molecular weight of 40,000 or lower, and contains a drug for treating or preventing a vitreoretinal disease. The high-molecular weight polylactic acid and the low-molecular weight polylactic acid are in a blending ratio of preferably 90/10 to 50/50, more preferably 90/10 to 70/30, and most preferably 80/20. The molecular weight of the high-molecular weight polylactic acid is preferably 40,000 to 200,000. The molecular weight of the low-molecular weight polylactic acid is preferably 3,000 to 40,000, and more preferably 5,000 to 20,000. The drug is, for example, an antiulcer agent, an antiviral agent, an anti-inflammatory agent, an antifungal agent or an antimicrobial.