7-hexanoyltaxol and methods for preparing the same

1. Field of the Invention An antitumor compound of formula (5): Also provided by the present invention is a method of preparing a compound of formula (5) whereby diesterification of the alcohol groups located at the 2′and 7 positions of paclitaxel is followed by the hydrolysis of the 2′hexanoate gro...

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Bibliographische Detailangaben
Hauptverfasser: Murray, Christopher K, Zheng, Qun Y, Shakya, Sagar R
Format: Patent
Sprache:eng
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Zusammenfassung:1. Field of the Invention An antitumor compound of formula (5): Also provided by the present invention is a method of preparing a compound of formula (5) whereby diesterification of the alcohol groups located at the 2′and 7 positions of paclitaxel is followed by the hydrolysis of the 2′hexanoate group resulting in 7-hexanoyltaxol.