Combination effective for the treatment of impotence

This invention relates to the treatment of impotence comprising co-administering (1) a potassium channel opener and (2) a compound which elevates cyclic guanosine 3′,5′-monophosphate (cGMP) levels. The combination is particularly suitable for the treatment of patients suffering from impotence or ere...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: Maytom, Murray C
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:This invention relates to the treatment of impotence comprising co-administering (1) a potassium channel opener and (2) a compound which elevates cyclic guanosine 3′,5′-monophosphate (cGMP) levels. The combination is particularly suitable for the treatment of patients suffering from impotence or erectile dysfunction. This invention relates to the treatment of erectile dysfunction with a combination of (1) a compound selected from potassium channel openers, and (2) a compound selected from compounds which elevate cGMP levels. Sildenafil or a pharmaceutically acceptable salt thereof is preferred as the cGMP PDE elevator. Also included are compositions and kits comprising such impotence treating compounds.