Bicyclic antagonists selective for the v 3 integrin

This invention relates to a series of tetrahydro- and dihydroquinoline, tetrahydronaphthalene and tetrahydro-5H-benzocycloheptene bicyclic compounds of Formulae (I) and (II) and non-toxic salts thereof, which selectively antagonize the integrin while minimally inhibiting platelet aggregation mediate...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zask, Arie, Hauze, Diane Barbara, Kees, Kenneth Lewis, Coghlan, Richard Dale, Yardley, John
Format: Patent
Sprache:eng
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