Peptidyl calcium channel blockers

The present invention relates to compounds that act to block calcium channels; methods of using the compounds to treat stroke, cerebral ischemia, pain, head trauma or epilepsy; and to pharmaceutical compositions that contain the compounds of the present invention. The present invention provides comp...

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Bibliographische Detailangaben
Hauptverfasser:	Booth, Richard John, Brogley, Louis, Cody, Wayne Livingston, Connor, David Thomas, Hamilton, Harriet Wall, He, John Xiaoqiang, Hu, Lain-Yen, Lescosky, Leonard Joseph, Malone, Thomas Charles, Nadasdi, Laszlo, Rafferty, Michael Francis, Roth, Bruce David, Silva, Diego F, Song, Yuntao, Szoke, Balazs G, Urge, Laszlo
Format:	Patent
Sprache:	eng
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The present invention relates to compounds that act to block calcium channels; methods of using the compounds to treat stroke, cerebral ischemia, pain, head trauma or epilepsy; and to pharmaceutical compositions that contain the compounds of the present invention. The present invention provides compounds that block calcium channels having the Formula I shown below. The present invention also provides methods of using the compounds of Formula I to treat stroke, cerebral ischemia, head trauma, or epilepsy and to pharmaceutical compositions that contain the compounds of Formula I.