Synthesis of carbamate ketolide antibiotics

This invention relates to a preparation of macrolide antibiotics that are useful as antibacterial and antiprotozoal agents in mammals, including man, as well as in fish and birds. The invention relates to a method of preparing a macrolide antibiotic of the formula wherein R, R, R, R, Rare defined ab...

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Hauptverfasser: Ripin, David H. B, Vanderplas, Brian C, Kaneko, Takushi, McMillen, William T, McLaughlin, Robert W
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:This invention relates to a preparation of macrolide antibiotics that are useful as antibacterial and antiprotozoal agents in mammals, including man, as well as in fish and birds. The invention relates to a method of preparing a macrolide antibiotic of the formula wherein R, R, R, R, Rare defined above. These antibiotics are useful as antibacterial and antiprotozoal agents in mammals, including man, as well as in fish and birds. The invention also includes novel compounds made by the preparation of the macrolide antibiotic.