Method for identifying or screening agonist and antagonist to PPAR
1. Technical Field A method for identifying or screening an agonist for or antagonist to a peroxisome proliferator activated receptor (PPAR) which comprises allowing a test cell and a substance to be tested to coexist, and detecting a change in a ligand-dependent interaction between the PPAR and a c...
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creator | Taniguchi, Tomoyasu Mizukami, Junko |
description | 1. Technical Field
A method for identifying or screening an agonist for or antagonist to a peroxisome proliferator activated receptor (PPAR) which comprises allowing a test cell and a substance to be tested to coexist, and detecting a change in a ligand-dependent interaction between the PPAR and a coactivator in the test cells due to the substance to be tested by measuring the expression of a reporter gene as an index. |
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A method for identifying or screening an agonist for or antagonist to a peroxisome proliferator activated receptor (PPAR) which comprises allowing a test cell and a substance to be tested to coexist, and detecting a change in a ligand-dependent interaction between the PPAR and a coactivator in the test cells due to the substance to be tested by measuring the expression of a reporter gene as an index.</description><language>eng</language><creationdate>2002</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6365361$$EPDF$$P50$$Guspatents$$Hfree_for_read</linktopdf><link.rule.ids>230,308,776,798,881,64012</link.rule.ids><linktorsrc>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6365361$$EView_record_in_USPTO$$FView_record_in_$$GUSPTO$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Taniguchi, Tomoyasu</creatorcontrib><creatorcontrib>Mizukami, Junko</creatorcontrib><creatorcontrib>Tanabe Seiyaku Co., Ltd</creatorcontrib><title>Method for identifying or screening agonist and antagonist to PPAR</title><description>1. Technical Field
A method for identifying or screening an agonist for or antagonist to a peroxisome proliferator activated receptor (PPAR) which comprises allowing a test cell and a substance to be tested to coexist, and detecting a change in a ligand-dependent interaction between the PPAR and a coactivator in the test cells due to the substance to be tested by measuring the expression of a reporter gene as an index.</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2002</creationdate><recordtype>patent</recordtype><sourceid>EFH</sourceid><recordid>eNrjZHDyTS3JyE9RSMsvUshMSc0ryUyrzMxLVwByi5OLUlPzQJzE9Py8zOIShcS8FCAugXFL8hUCAhyDeBhY0xJzilN5oTQ3g4Kba4izh25pcUFiCdDI4vj0okQQZWBmbGZqbGZoTIQSAOZNMoo</recordid><startdate>20020402</startdate><enddate>20020402</enddate><creator>Taniguchi, Tomoyasu</creator><creator>Mizukami, Junko</creator><scope>EFH</scope></search><sort><creationdate>20020402</creationdate><title>Method for identifying or screening agonist and antagonist to PPAR</title><author>Taniguchi, Tomoyasu ; Mizukami, Junko</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-uspatents_grants_063653613</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2002</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Taniguchi, Tomoyasu</creatorcontrib><creatorcontrib>Mizukami, Junko</creatorcontrib><creatorcontrib>Tanabe Seiyaku Co., Ltd</creatorcontrib><collection>USPTO Issued Patents</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Taniguchi, Tomoyasu</au><au>Mizukami, Junko</au><aucorp>Tanabe Seiyaku Co., Ltd</aucorp><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Method for identifying or screening agonist and antagonist to PPAR</title><date>2002-04-02</date><risdate>2002</risdate><abstract>1. Technical Field
A method for identifying or screening an agonist for or antagonist to a peroxisome proliferator activated receptor (PPAR) which comprises allowing a test cell and a substance to be tested to coexist, and detecting a change in a ligand-dependent interaction between the PPAR and a coactivator in the test cells due to the substance to be tested by measuring the expression of a reporter gene as an index.</abstract><oa>free_for_read</oa></addata></record> |
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title | Method for identifying or screening agonist and antagonist to PPAR |
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