Validation process for permeation measurements through closed containers

This invention relates to a process for validating permeation measurements made through closed containers; more particularly, the process is useful in validating permeation measurements through materials forming closed containers, where the containers have one or more closure members which may contribute to leakage and may therefore be a source of error in the permeation measurements. A method for validating permeation measurements through closed containers including closure members, by making a first measurement of permeation through a container of a first size, and making a second measurement of permeation through a container of a second size, both with the same closure members, and subtracting the permeation measurement contributions respectively made by the closure members.