Synthesis of carboxamides from the catalyzed reaction of aldehydes and amines

The present invention relates to a process for the synthesis of amides from the reaction of an aldehyde with a primary or secondary amine in the presence of a catalyst and suitable additives and solvents. The catalyst is a metal complex, which may be in the form of a metal-ligand complex or metal pr...

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Bibliographische Detailangaben
Hauptverfasser: Bei, Xiaohong, Guram, Anil
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to a process for the synthesis of amides from the reaction of an aldehyde with a primary or secondary amine in the presence of a catalyst and suitable additives and solvents. The catalyst is a metal complex, which may be in the form of a metal-ligand complex or metal precursor/ligand composition. Aldehydes are catalytically combined with amines to form carboxamides in one step using an oxidant and a metal-ligand complex or metal/ligand composition.