Thiophenylthiopyrane dioxides as mmp or tnf-alpha inhibitors

A compound of the formula: in which R 1 is optionally substituted phenyl, optionally substituted naphthyl, optionally substituted bicyclic heterocyclic group, optionally substituted lower alkenyl or optionally substituted lower alkynyl, and R 2 is carboxy or protected carboxy, or a salt thereof, use...

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Bibliographische Detailangaben
Hauptverfasser: Neya, Masahiro, Sawada, Akihiko, Ohne, Kazuhiko, Abe, Yoshito, Mizutani, Tsuyoshi, Ishibashi, Naoki, Inoue, Makoto
Format: Patent
Sprache:eng
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Zusammenfassung:A compound of the formula: in which R 1 is optionally substituted phenyl, optionally substituted naphthyl, optionally substituted bicyclic heterocyclic group, optionally substituted lower alkenyl or optionally substituted lower alkynyl, and R 2 is carboxy or protected carboxy, or a salt thereof, useful for treating and/or preventing MMP- or TNF- mediated diseases. 1