Rodent with urinary disturbance and method of constructing the same, and method of screening remedy for urinary disturbance using the rodent

It is intended to provide an animal model of urinary dysfunction induced by damage in brain nerve tissue in a small animal conveniently and at a high reproducibility. A rat in which the central urinary function alone is specifically damaged by regionally injuring the brain superior colliculus with t...

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Bibliographische Detailangaben
Hauptverfasser: Sakai, Miyuki, Kubota, Atsuhiko, Hanada, Takahisa
Format: Patent
Sprache:eng
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Zusammenfassung:It is intended to provide an animal model of urinary dysfunction induced by damage in brain nerve tissue in a small animal conveniently and at a high reproducibility. A rat in which the central urinary function alone is specifically damaged by regionally injuring the brain superior colliculus with the use of a legion generator. The animal model of urinary dysfunction is useful in a method of screening a therapeutic agent for urinary dysfunction.