Sulfone derivatives as 5-HT7 receptor ligands

Sulfone derivatives as 5-HT7 receptor ligands

The present invention relates to sulfone derivatives of formula (I): Ar-SO 2 -CR 2 R 3 -L-N(R 1 ) 2   I wherein Ar, L, R 1 , R 2 and R 3 are as defined herein, and pharmaceutically acceptable salts and N-oxides thereof, useful in the treatment of a condition which is susceptible to treatment by modu...

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Bibliographische Detailangaben
Hauptverfasser: Hunt, Peter, Bourrain, Sylvie, Huscroft, Ian, Kulagowski, Janusz, London, Clare, Naylor, Elizabeth, Raubo, Piotr, Seward, Eileen
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to sulfone derivatives of formula (I): Ar-SO 2 -CR 2 R 3 -L-N(R 1 ) 2   I wherein Ar, L, R 1 , R 2 and R 3 are as defined herein, and pharmaceutically acceptable salts and N-oxides thereof, useful in the treatment of a condition which is susceptible to treatment by modulation of 5-HT 7 receptor activity, such as depression or a sleep disorder.