Substituted anilide ligands for the thyroid receptor
Novel thyroid receptor ligands are provided having the general formula I 1 wherein X, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , R 10 , R 11 , R 12 and R 13 are as defined herein. In addition, a method is provided for preventing, inhibiting or treating diseases or disorders associated wit...
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Format: | Patent |
Sprache: | eng |
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Zusammenfassung: | Novel thyroid receptor ligands are provided having the general formula I
1
wherein
X, R
1
, R
2
, R
3
, R
4
, R
5
, R
6
, R
7
, R
8
, R
9
, R
10
, R
11
, R
12
and R
13
are as defined herein.
In addition, a method is provided for preventing, inhibiting or treating diseases or disorders associated with metabolic dysfunction or which are dependent upon the expression of a T
3
regulated gene, wherein a compound as described above is administered in a therapeutically effective amount. |
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