Bioavailable fenofibrate compositions, methods for treating hyperlipidemia and hypercholesterolemia and processes for the preparation of such compositions
Pharmaceutical compositions for treating hyperlipidemia or hypercholesterolemia in mammals are described which comprise: 1 (a) fenofibrate 5 to 35 wt. -% (b) a cyclodextrin 4 to 30 wt. -% (c) an alkali metal or 0.1 to 10 wt. -%; and alkaline earth metal docusate and/or alkali metal or alkaline e...
Gespeichert in:
Hauptverfasser: | , , , |
---|---|
Format: | Patent |
Sprache: | eng |
Online-Zugang: | Volltext bestellen |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Zusammenfassung: | Pharmaceutical compositions for treating hyperlipidemia or hypercholesterolemia in mammals are described which comprise:
1
(a)
fenofibrate
5 to 35 wt. -%
(b)
a cyclodextrin
4 to 30 wt. -%
(c)
an alkali metal or
0.1 to 10 wt. -%; and
alkaline earth metal docusate and/or
alkali metal or alkaline earth metal
lauryl sulfate
(d)
a water-insoluble, wettable
5 to 30 wt. -%
inorganic carrier capable of forming a
dispersion of the fenofibrate
and a pharmaceutically acceptable
inert carrier or diluent.
A therapeutically effective amount of the compositions are orally administered to mammals to treat hyperlipidemia or hypercholesterolemia. |
---|