Novel clock gene promoter

The present invention discloses a Period2 gene promoter, a construct containing the promoter and a reporter gene, a cell containing the construct, a transgenic animal harboring the construct, and a method for screening a substance which controls expression or oscillatory expression of a biological c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Takasugi, Tomohiro, Chen, Wenbin, Hashimoto, Seiichi
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention discloses a Period2 gene promoter, a construct containing the promoter and a reporter gene, a cell containing the construct, a transgenic animal harboring the construct, and a method for screening a substance which controls expression or oscillatory expression of a biological clock gene. The screening method uses the above cell, a suprachiasmatic nucleus section or peripheral tissue of the above transgenic animal or the above transgenic animal.