Process for the preparation of omega-benzyl esters of amino diacids and of alkanesulphonates of these esters, and these alkanesulphonates

The invention relates to a process for the preparation of an -benzyl ester of an amino diacid, characterized in that the amino diacid is reacted with a benzyl alcohol derivative of formula (I) 1 in which the R 1 substituent or substituents, which are identical or different, represent a hydrogen atom...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Vitrant, Anne, Ferruccio, Laurence, Vincent, Charles-Henry
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to a process for the preparation of an -benzyl ester of an amino diacid, characterized in that the amino diacid is reacted with a benzyl alcohol derivative of formula (I) 1 in which the R 1 substituent or substituents, which are identical or different, represent a hydrogen atom, a C 1 to C 4 alkyl group, a C 1 to C 4 alkoxy group or a halogen atom and n is equal to 1, 2 or 3, in the presence of at least one mol per mole of the amino diacid of an alkanesulphonic acid, optionally in the presence of a solvent. The intermediate alkanesulphonates of the -benzyl esters of amino diacids and the -benzyl esters of amino diacids are obtained with a good yield and an excellent purity by virtue of this process.