Concentrate of a factor VIII:C-containing von Willebrand factor and the process relating thereto

Concentrate of a factor VIII:C-containing von Willebrand factor and the process relating thereto

The invention relates to a concentrate and a process for producing a factor VIII:C-containing von Willebrand factor by fractional precipitation from a liquid comprising factor VIII:C and von Willebrand factor, resulting in an increased content of high molecular weight multimers of von Willebrand fac...

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Bibliographische Detailangaben
Hauptverfasser: Juraschek, Manfred, Kumpe, Gerhardt, Mayer, Natascha, Schulte, Stefan, Wormshabacher, Wilfried
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to a concentrate and a process for producing a factor VIII:C-containing von Willebrand factor by fractional precipitation from a liquid comprising factor VIII:C and von Willebrand factor, resulting in an increased content of high molecular weight multimers of von Willebrand factor and a ratio of the vWF:RCoF activity to vWF:Ag of greater than 1.