Hydroxamic acid or n-formyl hydroxylamine derivatives as inhibitors of bakterial polypeptide deformylase for treating microbial infections
1 Compounds of formula (I) are antibacterial or antiprotozoal agents for treatment of infections in humans and non-human mammals, wherein: Z represents a radical of formula -N(OH)CH( O) or formula C( O)NH(OH); R 1 represents hydrogen, methyl or trifluromethyl, or except when Z is a radical of formul...
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| Sprache: | eng |
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Compounds of formula (I) are antibacterial or antiprotozoal agents for treatment of infections in humans and non-human mammals, wherein: Z represents a radical of formula -N(OH)CH( O) or formula C( O)NH(OH); R
1
represents hydrogen, methyl or trifluromethyl, or except when Z is a radical of formula -N(OH)( O), a hydroxy, halo or am group; R
2
represents a group R
10
-(X)
n
-(ALK)
m
- wherein R
10
, ALK, X, m and n are as defined in the specification; R
3
represents hydrogen, (C
1
-C
6
) alkyl or phenyl(C
1
-C
6
)alkyl-; and R
5
and R
6
are as defined in the specification. |
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