Parp inhibitors

Parp inhibitors

The present invention provides compounds comprising a bicyclic aryl moiety, such as 2H-phthalazin-1-one or derivatives thereof, compositions comprising the same, and methods for producing and using the same. In particular, the present invention provides compounds of the formula: 1 or a pharmaceutica...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Beaton, Graham, Moree, Wilna, Rueter, Jaimie, Dahl, Russell, McElligott, David, Goldman, Phyllis, Demaggio, Anthony, Christenson, Erik, Herendeen, Dan, Fowler, Kerry, Huang, Danwen, Bertino, Jaimie, Bourdon, Lisa, Fairfax, David, Jiang, Qin, Reisch, Helge, Song, Ren, Zhichkin, Pavel
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides compounds comprising a bicyclic aryl moiety, such as 2H-phthalazin-1-one or derivatives thereof, compositions comprising the same, and methods for producing and using the same. In particular, the present invention provides compounds of the formula: 1 or a pharmaceutically acceptable salt, a hydrate, a solvate, or a prodrug thereof; where Q 1 , Q 2 and Y are those defined herein.