Process for the preparation of amorphous atorvastatin calcium

Process for the preparation of amorphous atorvastatin calcium

A process is disclosed for the preparation of amorphous atorvastatin calcium which comprises dissolving crude atorvastatin calcium in a lower alkanol containing 2 to 4 carbon atoms or a mixture of such alkanols under heating and, after cooling, isolating the precipitated amorphous atorvastatin calci...

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Bibliographische Detailangaben
Hauptverfasser: Greff, Zoltan, Kotay Nagy, Peter, Barkoczy, Jozsef, Simig, Gyula, Balazs, Laszlo, Doman, Imre, Ratkai, Zoltan, Seres, Peter, Szent Kirallyi, Zsuzsa, Barta, Ferenc, Vereczkeyne Donath, Gyorgyi, Nagy, Kalman
Format: Patent
Sprache:eng
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Zusammenfassung:A process is disclosed for the preparation of amorphous atorvastatin calcium which comprises dissolving crude atorvastatin calcium in a lower alkanol containing 2 to 4 carbon atoms or a mixture of such alkanols under heating and, after cooling, isolating the precipitated amorphous atorvastatin calcium.