Derivatives of naphthalene with comt inhibiting activity

Derivatives of naphthalene with comt inhibiting activity

Compounds of formula (I′), wherein A, R 1 to R 3 and t are as defined in the disclosure, exhibit COMT enzyme inhibiting activity so that they are useful as COMT inhibitors.

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Bibliographische Detailangaben
Hauptverfasser: Bäckström, Reijo, Pystynen, Jarmo, Lotta, Timo, Ovaska, Martti, Taskinen, Jyrki
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Compounds of formula (I′), wherein A, R 1 to R 3 and t are as defined in the disclosure, exhibit COMT enzyme inhibiting activity so that they are useful as COMT inhibitors.