Nucleic acid switch patterns as cell or tissue type identifiers

Methods are provided for characterizing a developmental or lineage-specific cell type or other cell types by analyzing nucleic acid switch patterns or profiles and/or proteins indicative of these switches. Such a method can include, for example, comparing the nucleic acid of the cell with nucleic ac...

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Bibliographische Detailangaben
Hauptverfasser: Roman-Dreyer, Janet, Dreyer, William
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Methods are provided for characterizing a developmental or lineage-specific cell type or other cell types by analyzing nucleic acid switch patterns or profiles and/or proteins indicative of these switches. Such a method can include, for example, comparing the nucleic acid of the cell with nucleic acid from a corresponding germline cell or other cell, wherein a difference in the nucleic acid is indicative of a nucleic acid switch. Optionally, the cell type can be further characterized in terms of developmental or lineage specific cell type.