Phthalazinone derivatives
A compound of formula: 1 or an isomer, salt, solvate, chemically protected form, or prodrug thereof, wherein A and B together represent an optionally substituted, fused aromatic ring; R L is a C 5-7 aryl group substituted in the meta position by the group R 2 , and optionally further substituted; wh...
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| Format: | Patent |
| Sprache: | eng |
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| Zusammenfassung: | A compound of formula:
1
or an isomer, salt, solvate, chemically protected form, or prodrug thereof, wherein A and B together represent an optionally substituted, fused aromatic ring; R
L
is a C
5-7
aryl group substituted in the meta position by the group R
2
, and optionally further substituted; wherein R
2
is selected from:
2
and its use as a pharmaceutical, in particular for the treatment of diseases ameliorated by inhibiting the activity of PARP. |
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