Molecules for diagnostics and therapeutics

The present invention provides purified human polynucleotides for diagnostics and therapeutics (dithp). Also encompassed are the polypeptides (DITHP) encoded by dithp. The invention also provides for the use of dithp, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	Lincoln, Stephen, Hodgson, David, Russo, Frank, Albany, Peter, Banville, Steve, Bratcher, Shawn, Dufour, Gerard, Cohen, Howard, Rosen, Bruce, Chalup, Michael, Jackson, Jennifer, Jones, Anissa, Yu, Jimmy, Greenawalt, Lila, Panzer, Scott, Roseberry Lincoln, Ann, Wright, Rachel, Daniels, Susan
Format:	Patent
Sprache:	eng
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The present invention provides purified human polynucleotides for diagnostics and therapeutics (dithp). Also encompassed are the polypeptides (DITHP) encoded by dithp. The invention also provides for the use of dithp, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing dithp for the expression of DITHP. The invention additionally provides for the use of isolated and purified DITHP to induce antibodies and to screen libraries of compounds and the use of anti-DITHP antibodies in diagnostic assays. Also provided are microarrays containing dithp and methods of use.