Process for the conversion of penam ring system to cepham ring system

The present invention relates to a new process for the preparation of cephalosporin derivative of formula (I) 1 wherein R 1 represents p-methoxybenzyl, p-nitrobenzyl, o-chlorobenzyl or diphenylmethyl; R 2 represents CH 3 or CR a R b COOR c where R a and R b independently represent hydrogen or methyl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Palanisamy, Senthilkumar, Deshpande, Pandurang, Ramar, Padmanabhan
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to a new process for the preparation of cephalosporin derivative of formula (I) 1 wherein R 1 represents p-methoxybenzyl, p-nitrobenzyl, o-chlorobenzyl or diphenylmethyl; R 2 represents CH 3 or CR a R b COOR c where R a and R b independently represent hydrogen or methyl and R c represents hydrogen or (C 1 -C 6 ) alkyl; R 3 represents hydrogen, acyl, phenacyl, formyl or trityl group.